Taking on the challenge are Catríiona Tierney, breakfast-time presenter with Limerick 95; Keith Cunningham, drive-time presenter with Red FM; Jimmy Norman, Galway Bay FM's breakfast presenter and Jenny Green from Dublin FM 104.
All of the participants have been in training for the event. They have worked closely with a dietician and slept as much as possible to build up their energy reserves. The current record is held by Martin Boss, an American DJ, who played for 72 hours straight in Orlando, Florida.
DJ Freeze, a Dutch native whose real name is Lodewijk Verminnen, decided to go for a world record of 75 hours, staging the event at a DJ school in Groningen, Holland.
Sadly, history was not on DJ Freeze's side, and despite a strong start, he physically collapsed after 71 hours. Catríona, who will be operating between a nightclub and bar in Limerick, said her longest-ever DJ stint up to now was around eight hours and pointed out that the record-breaking guidelines were pretty tough.
"You can only take a 15-minute break every eight hours; you can't repeat the same song in any given four-hour set and you can't take more than a 10-second gap between songs," she pointed out.
To keep going, Catríiona will be eating a little and often mostly bananas and pasta. Coffee and tea is out, not just because it is dehydrating but because it will mean more trips to the loo. Catríona is already well used to working almost around the clock. As well as her radio work, she also helps bring out the Limerick Post and has her own weekly social column called After Dark.
"I don't get a lot of sleep as it is, but for the last week I have been trying to get as much rest as possible."
All of the DJs have been checked by a doctor to ensure they are up for the challenge, and they will be regularly checked during the record attempt to make sure their health does not suffer. Paddy Power Bookmakers have put odds on the four DJs' chances of who will be first out and, unfortunately, Catríona is reckoned to be first to quit spinning at 2/1, although she hopes to defy the odd.
The odds on Jenny Green's giving up the challenge is 9/4, while Keith Cunningham's staying power is put at 3/1 and Jimmy Norman's at 11/4.
The event is in aid of the charities of Operation Rudolph Alzheimers Society of Ireland; Chernobyl Children's Project, and the 2003 Special Olympics World Games.