Top seed and defending champion Justine Henin-Hardenne of Belgium became the highest-seeded player at this year’s US Open to lose as she was knocked out by Russia’s Nadia Petrova.

Top seed Roger Federer remains on course to win his third Grand Slam of the year after advancing to the quarter-finals at Flushing Meadows thanks to a walkover.

Andre Agassi played down talk of his imminent retirement after booking his place in the third round of the US Open at Flushing Meadow.

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