A US drone has fired two missiles at a vehicle in north west Pakistan, killing four suspected militants.

Pakistan is reopening supply lines into Afghanistan after the US issued an apology for the November killing of 24 Pakistani troops in a Nato airstrike, the Obama administration said.

The Pakistani militant leader with a $10m (€7.6m) bounty on his head has mocked America and dared it to arrest him.

The outcome of any talks on ending the bloodshed in Syria must not be predetermined, said Russian foreign minister Sergei Lavrov, sticking to Moscow’s opposition to Western and Arab pressure for President Bashar al-Assad to cede power.

Pakistan’s foreign minister has lashed out at the US for accusing the country’s most powerful intelligence agency of supporting extremist attacks against American troops in Afghanistan.