JONJO O’NEILL has raised the possibility of Synchronised running in the Lexus Chase at Leopardstown rather than defending his Welsh National title over Christmas.

JONJO O’NEILL’S Synchronised, the Welsh Grand National winner, heads a 51-strong list of initial acceptors for the €250,000 Ladbrokes’ Irish Grand National at Fairyhouse on Easter Monday.

AN Irish-made drug used to lower the heart rate in people with heart disease can help reduce the risk of heart attack by more than 40%, according to new research.

The new owners of Boots, Stefano Pessina and private equity firm Kohlberg Kravis Roberts, today said the group was trading "well ahead" of expectations after being taken private for £11.1 billion in July.