Clare will field a team containing three Championship newcomers when they clash with Tipperary in Sunday's Munster SHC semi-final at the Gaelic Grounds (throw-in 4pm).
Wing back Patrick O'Connor and forwards Cathal McInerney and Conor McGrath are the new men in, with O'Connor and McGrath having played for Clare against Tipp in last year's Munster U-21 final.
In all, Clare boss Ger O'Loughlin has made four changes in personnel to the side that lost the Allianz Hurling League Division 2 final to Limerick last month.
Philip Brennan is the starting goalkeeper in place of Donal Tuohy, while James McInerney, who will line out at centre-back, is an indirect replacement for back injury victim Domhnall O'Donovan.
With Liam Markham nursing a broken finger, Jonathan Clancy joins Nicky O'Connell in midfield and debutant McInerney has been added to the half-forward line.
The final change sees the highly-rated Darach Honan pencilled in at full-forward after battling with a groin injury. Colin Ryan is the player to lose out.
Clare last reached the Munster final in 2008. Indeed, it is three years since the Banner men last recorded a provincial Championship win - they were beaten by Tipperary at this stage in 2009 and twelve months ago Waterford got the better of them in the last four.
In the 2008 Munster decider, Clare suffered a 2-21 to 0-19 defeat to Tipp despite the best efforts of Niall Gilligan (0-8) and Mark Flaherty and Colin Lynch (0-3 each).
CLARE (SHC v Tipperary): Philip Brennan; Pat Vaughan (capt), Conor Cooney, Cian Dillon; Patrick O'Connor, James McInerney, Patrick Donnellan; Nicky O'Connell, Jonathan Clancy; John Conlon, Fergal Lynch, Cathal McInerney; Diarmuid McMahon, Darach Honan, Conor McGrath.
Subs: Donal Tuohy, Eamon Glynn, Mark Earley, Brendan Bugler, Cathal Chaplin, Gerry Quinn, Sean Collins, Colin Ryan, Liam Markham, Caimin Morey, Cormac O'Donovan.