Here’s the lowdown on four big games across Europe...
England v Argentina, Twickenham, 2.30pm.
England make four changes from the starting XV that beat Fiji, with George Kruis and Tom Wood back in the pack. Kruis returns from ankle surgery to replace the banned Joe Launchbury while Wood ousts flanker Teimana Harrison. Mike Brown is in for Alex Goode at full-back, while Jonny May displaces Semesa Rokoduguni on the right wing. Argentina make three changes from the team that lost to Scotland, one of which sees Leonardo Senatore replacing Facundo Isa at number eight. In the backs, Tomas Cubelli replaces scrum-half Martin Landajo, who drops to the bench, and Santiago Gonzalez Iglesias comes in at centre. The experienced Juan Martin Hernandez switches to fly-half in place of Nicolas Sanchez, who has an ankle injury.
M Brown (Harlequins); J May (Gloucester), J Joseph (Bath), O Farrell (Saracens), E Daly (Wasps); G Ford (Bath), B Youngs (Leicester); M Vunipola (Saracens), D Hartley (Northampton, capt), D Cole (Leicester), C Lawes (Northampton), G Kruis (Saracens), C Robshaw (Harlequins), T Wood (Northampton), B Vunipola (Saracens).
J George (Saracens), J Marler (Harlequins), K Sinckler (Harlequins), C Ewels (Bath), T Harrison (Northampton), D Care (Harlequins), B Te’o (Worcester), H Slade (Exeter).
J Tuculet; M Orlando, M Moroni, S Gonzalez Iglesias, S Cordero; J M Hernandez, T Cubelli; L Noguera, A Creevy (capt), R Herrera, G Petti, M Alemanno, P Matera, J Ortega Desio, L Senatore.
J Montoya, S Garcia Botta, E Pieretto, F Isa, T Lezana, M Landajo, J De La Fuente, J P Estelles.
Scotland v Georgia, Rugby Park, 2.30pm.
Scotland coach Vern Cotter has opted for experience on Saturday, with his five changes adding 125 caps to the side that beat Argentina last week. Olympic silver medallist Mark Bennett comes in at centre for Huw Jones, who injured a foot last weekend. In the pack, Ross Ford, Richie Gray, Rob Harley and Ryan Wilson all start. Giorgi Aptsiauri is recalled on the wing for Georgia, with Tamaz Mchedlidze moving to centre and Giorgi Koshadze dropped from the squad.
S Hogg (Glasgow); S Maitland (Saracens), M Bennett (Glasgow), A Dunbar (Glasgow), T Seymour (Glasgow); F Russell (Glasgow), G Laidlaw (Gloucester, capt); A Dell (Edinburgh), R Ford (Edinburgh), Z Fagerson (Glasgow), R Gray (Toulouse), J Gray (Glasgow), R Harley (Glasgow), H Watson (Edinburgh), R Wilson (Glasgow).
F Brown (Glasgow), A Allan (Glasgow), M Low (Exeter), G Gilchrist (Edinburgh), J Barclay (Scarlets), A Price (Glasgow), P Horne (Glasgow), R Hughes (Glasgow).
M Kvirikashvili; G Aptsiauri, M Sharikadze, T Mtchedlidze, S Todua; L Malaghuradze, V Lobzhanidze; M Nariashvili, J Bregvadze, L Chilachava, K Mikautadze, G Nemsadze, V Kolelishvili, M Gorgodze (capt), B Bitsadze.
B Alkhazashvili, K Asieshvili, D Kubriashvili, L Lomidze, G Tkhilaishvili, G Begadze, B Tsiklauri, S Sutiashvili.
Wales v South Africa, Principality Stadium, 5.30pm.
Sam Warburton misses the game after suffering an injury in training. His place in the back-row is taken by Dan Lydiate, with Justin Tipuric restored to the open-side and Taulupe Faletau on the bench after injury. Leigh Halfpenny moves to full-back after playing on the wing in the 33-30 win over Japan. Scott Williams is preferred at centre to Jamie Roberts in a side showing one change from the win over Argentina.
Loose-head Gethin Jenkins is captain after recovering from a shoulder injury.
South Africa have dropped iconic winger Bryan Habana. Debutant Jamba Ulengo replaces Habana, while centre Rohan Janse van Rensburg and back-row Uzair Cassiem also win their first caps.
L Halfpenny (Toulon); G North (Northampton), J Davies (Scarlets), S Williams (Scarlets), Liam Williams (Scarlets); D Biggar (Ospreys), G Davies (Scarlets); G Jenkins (Cardiff Blues, capt), K Owens (Scarlets), T Francis (Exeter), L Charteris (Bath), A W Jones (Ospreys), D Lydiate (Ospreys), J Tipuric (Ospreys), R Moriarty (Gloucester).
S Baldwin (Ospreys), N Smith (Ospreys), S Lee (Scarlets), C Hill (Newport Gwent Dragons), T Faletau (Bath), Lloyd Wiliams (Cardiff Blues), S Davies (Ospreys), J Roberts (Harlequins).
J Goosen; R Combrinck, F Venter, R Janse van Rensburg, J Ulengo; E Jantjies, F de Klerk; T Mtawarira, A Strauss (capt), L Adriaanse, P S du Toit, L de Jager, N Carr, U Cassiem, W Whiteley.
M Marx, S Kitshoff, T Nyakane, F Mostert, J-L du Preez, P van Zyl, P Lambie, L Mapoe.
France v New Zealand, Stade de France, 8pm.
New Zealand have dropped scrum-half Aaron Smith in favour of TJ Perenara for Saturday’s Test against France in Paris, in one of five number of changes by head coach Steve Hansen. Camille Lopez will start at fly-half for France in their rugby union Test against world champions New Zealand on Saturday in one of three changes from the team that narrowly lost to the Wallabies.
Brice Dulin; Noa Nakaitaci, Remi Lamerat, Wesley Fofana, Virimi Vakatawa; Camille Lopez, Maxime Machenaud; X Chiocci, G Guirado, U Atonio, S Vahaamahina, Y Maestri, C Ollivon, K Gourdon, L Picamoles.
C Chat, C Baille, R Slimani, J Le Devedec, D Chouly, B Serin, JM Doussain, G Fickou.
I Dagg, W Naholo, A Lienert-Brown, R Crotty, J Savea, B Barrett, TJ Perenara; J Moody, D Coles, O Franks, B Retallick, S Whitelock,J Kaino, M Todd, K Read (captain) Replacements: C Taylor, W Crockett, C Faumuina, S Barrett, A Savea, A Smith, A Cruden, R Ioane.
C Taylor, W Crockett, C Faumuina, S Barrett, A Savea, A Smith, A Cruden, R Ioane.
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