Former Panamanian dictator Manuel Noriega has died at the age of 83, a source close to his family said.
There was no immediate information on the cause of his death, which happened late on Monday.
Panamanian President Juan Carlos Varela wrote in his Twitter account that "the death of Manuel A Noriega closes a chapter in our history".
The onetime US ally was ousted as Panama's dictator by an American invasion in 1989.
Noriega later served a 17-year drug sentence in the United States.
He spent the first two decades after his ousting in American and French jails and the final years of his life in a Panamanian prison for murder of political opponents during his 1983-89 regime.
Noriega accused Washington of a "conspiracy" to keep him behind bars and tied his legal troubles to his refusal to co-operate with a US plan aimed at toppling Nicaragua's leftist Sandinista government in the 1980s.
In recent years, Noriega had suffered various ailments, including high blood pressure and bronchitis.
In 2016, doctors detected the rapid growth of a benign brain tumour which had first been spotted four years earlier. In January this year, a court granted him house arrest to prepare for surgery on the tumour.
Noriega is survived by his wife, Felicidad, and daughters Lorena, Thays and Sandra.