A disruptive female passenger punched a pilot in the face after being ordered to leave his plane.
The woman was arrested at Manchester Airport before the departure of the easyJet flight to Cyprus on Wednesday.
The airline issued a statement which read: "EasyJet can confirm that the police were called to attend flight EZY1973 from Manchester to Paphos prior to its departure on 11 May to assist with a disruptive passenger.
"The passenger was subsequently arrested. The safety and well-being of passengers and crew is always easyJet's priority.
"Whilst such incidents are rare, we take them very seriously, do not tolerate abusive or threatening behaviour on board and always push for prosecution."
It is understood the woman attacked the captain of the plane as she was being led away.
The flight, which was due to depart at 2.10pm, eventually took off shortly before 4pm.
A Greater Manchester Police spokesman said: "At around 2.20pm on Wednesday 11 May police were called to a disturbance on a flight which was due to leave Manchester and fly to Paphos.
"On arrival police discovered a 25-year-old woman had been asked to leave the flight due to her behaviour.
"When being escorted by flight attendants from the aircraft, the woman assaulted the captain of the aircraft.
"The woman was arrested on suspicion of assault and officers also discovered she was wanted for drugs offences.
"The woman is now being questioned in police custody."