The Premier League starts this weekend with Jose Mourinho's troubled Man United making a trip to London to face West Ham in tomorrow's early game.
Saturday finishes off with the biggest clash of the weekend as Chelsea, fresh from their Carabao Cup victory over Liverpool during the week, welcoming the Reds back to Stamford Bridge for the 5.30pm kick-off.
The 3pm games include Arsenal hosting high-flying Watford, Chris Hughton's Brighton travelling to champions Man City and Spurs going to Huddersfield Town.
Burnley will face Cardiff in Sunday's 4pm kick-off, while Crystal Palace will have to wait until 8pm on Monday night for their clash with Bournemouth on the south coast.
Saturday, September 29
West Ham United v Manchester United, 12.30pm
Marko Arnautovic returns for West Ham against Manchester United, but Javier Hernandez misses out against his former club.
Arnautovic has recovered from the knee injury which forced him to sit out the goalless draw with Chelsea last weekend, but fellow forward Hernandez is still sidelined through illness.
"Marko is 💯% fit for tomorrow" 🙏 pic.twitter.com/sfHE1LxM64— West Ham United (@WestHam) September 28, 2018
Carlos Sanchez suffered a knee injury against Macclesfield in midweek and joins Jack Wilshere, Andy Carroll, Manuel Lanzini and Winston Reid in the treatment room.
Provisional squad: Fabianski, Adrian, Fredericks, Zabaleta, Ogbonna, Diop,
Balbuena, Rice, Cresswell, Masuaku, Obiang, Noble, Antonio, Yarmolenko, Snodgrass, Diangana, Anderson, Arnautovic, Perez.
Marcos Rojo and Sergio Romero are the only absentees as Manchester United head to West Ham, where Paul Pogba will be among the starters.
The boss has provided an update on Marcos Rojo's fitness... #MUFC— Manchester United (@ManUtd) September 28, 2018
Argentina defender Rojo has yet to play this season after returning from the World Cup injured and compatriot Romero serves a one-match ban for his sending off against Derby in the Carabao Cup.
United manager Jose Mourinho confirmed Pogba will start in east London while forward Marcus Rashford returns from a domestic ban.
Provisional squad: De Gea, Grant, Valencia, Dalot, Darmian, Young, Shaw, Smalling, Jones, Bailly, Lindelof, Pogba, Fellaini, Herrera, Mata, Matic, Pereira, Fred, McTominay, Lingard, Lukaku, Martial, Sanchez, Rashford
Arsenal v Watford, 3pm
Sokratis Papastathopoulos has recovered from a leg injury to return for Arsenal's Premier League clash against Watford on Saturday.
The Greece defender limped out of last week's win over Everton, but should be back in Unai Emery's side after missing the Carabao Cup tie with Brentford.
Sead Kolasinac was on the bench in midweek following a knee injury, but Laurent Koscielny (Achilles), Ainsley Maitland-Niles (leg), Carl Jenkinson (ankle) and Konstantinos Mavropanos (groin) are out.
Provisional squad: Cech, Leno, Bellerin, Lichtsteiner, Holding, Mustafi, Papastathopoulos, Kolasinac, Monreal, Xhaka, Elneny, Torreira, Guendouzi, Ramsey, Iwobi, Mkhitaryan, Ozil, Welbeck, Lacazette, Aubameyang.
Check back for Watford team news
Everton v Fulham, 3pm
Yerry Mina's wait to make his Everton debut continues after the defender was ruled out of Saturday's Premier League home clash with Fulham having suffered a stamp to the foot in training.
Toffees boss Marco Silva has said it is "nothing serious" and the hope is that summer signing Mina - who has been recovering from an injury to his other foot - will be back in training next week.
Seamus Coleman (foot) and Andre Gomes (hamstring) also remain unavailable, but Phil Jagielka could make his return to action after a knee injury.
Provisional squad: Pickford, Stekelenburg, Holgate, Baines, Keane, Zouma, Jagielka, Digne, Kenny, Gueye, Sigurdsson, Schneiderlin, Davies, Walcott, Tosun, Niasse, Bernard, Calvert-Lewin, Richarlison, Lookman.
Alfie Mawson faces a late fitness test before Fulham select their starting XI for Saturday's trip to Everton.
The defender is struggling with a back problem and could yet be replaced by the fit-again Tim Ream, who returned to Fulham's first team in Tuesday's 3-1 Carabao Cup victory at Millwall.
Midfielders Tom Cairney and Neeskens Kebano are expected to miss out again with ankle injuries.
Provisional squad: Bettinelli, Rico, Fabri, Fosu-Mensah, Christie, Odoi, Chambers, Mawson, Ream, Le Marchand, Bryan, Ayite, Ryan Sessegnon, Seri, McDonald, Johansen, De La Torre, Anguissa, Steven Sessegnon, Schurrle, Vietto, Mitrovic, Fonte, Kamara.
Huddersfield Town v Tottenham, 3pm
Huddersfield manager David Wagner will choose from an unchanged squad for the home game against Tottenham.
Wagner has no new injury problems, but midfielders Danny Williams and Ramadan Sobhi (both knee) remain sidelined.
Alex Pritchard is pushing for a recall against his former club, while fellow midfielder Jonathan Hogg and striker Steve Mounie could return.
Provisional squad: Lossl, Kongolo, Schindler, Jorgensen, Lowe, Durm, Billing, Hogg, Mooy, Hadergjonaj, Van La Parra, Mounie, Kachunga, Diakhaby, Depoitre, Mbenza, Hamer, Pritchard.
Tottenham must do without midfielder Christian Eriksen because of an abdominal problem.
Defender Serge Aurier will be assessed after picking up a thigh injury during the midweek Carabao Cup tie against Watford.
Goalkeepers Hugo Lloris (thigh) and Michel Vorm (knee) both continue their rehabilitation.
Provisional Squad: Gazzaniga, Trippier, Rose, Alderweireld, Vertonghen, Dier, Dembele, Alli, Moura, Son, Kane, Whiteman, Sanchez, Aurier, Winks, Lamela, Wanyama, Davies, Sissoko.
Manchester City v Brighton, 3pm
Manchester City will again be without Benjamin Mendy and Kevin De Bruyne for Saturday's Premier League clash with Brighton.
No date has yet been set for Mendy's probable return from a foot injury so Fabian Delph will continue to deputise.
De Bruyne has been sidelined for close to two months by a knee problem but is set to return to training in the next few days. Goalkeeper Claudio Bravo (Achilles) remains on the long-term injury list.
Provisional squad: Ederson, Muric, Grimshaw, Walker, Danilo, Stones, Otamendi, Kompany, Laporte, Delph, Zinchenko, Gundogan, Fernandinho, B Silva, D Silva, Mahrez, Sane, Sterling, Foden, Diaz, Aguero, Jesus.
Dale Stephens and Pascal Gross will miss Brighton's trip to Manchester City.
Stephens suffered a hamstring injury in Saturday's defeat to Tottenham, while fellow midfielder Gross remains sidelined with an ankle problem.
Colombia winger Jose Izquierdo is closer to his first appearance of the season after playing 45 minutes of an under-23 game on Monday.
Provisional squad: Ryan, Button, Steele, Bernardo, Montoya, Bruno, Bong, Dunk, Duffy, Balogun, Schelotto, Suttner, Bissouma, Propper, Kayal, Knockaert, March, Jahanbakhsh, Izquierdo, Andone, Locadia, Murray.
Newcastle United v Leicester City, 3pm
Newcastle striker Salomon Rondon is out of Saturday's Premier League clash with Leicester at St James' Park.
The on-loan West Brom forward damaged a thigh muscle during last weekend's 0-0 draw at Crystal Palace and will sit out as medics assess the extent of the injury, with Joselu likely to take his place.
Magpies boss Rafael Benitez otherwise has no fresh injury concerns with only long-term absentee Florian Lejeune (knee ligaments) missing.
Provisional squad: Dubravka, Darlow, Yedlin, Dummett, Manquillo, Sterry, Lascelles, Clark, Fernandez, Schar, Shelvey, Hayden, Diame, Ki, Ritchie, Kenedy, Murphy, Atsu, Longstaff, Perez, Muto, Joselu.
Leicester will be without Demarai Gray when they travel to Newcastle, with the winger set for up to six weeks out through injury.
Gray (ankle) was carried off on a stretcher during the Carabao Cup win against Wolves and joins midfielder Matty James (Achilles) on the sidelines.
Kasper Schmeichel and Harry Maguire were rested at Molineux and will return to the starting line-up, while captain Wes Morgan is available again in the Premier League after serving his one-match suspension against Huddersfield.
Provisional squad: Schmeichel, Ward, Jakupovic, Simpson, Chilwell, Morgan, Evans, Maguire, Pereira, Soyuncu, Fuchs, Benalouane, Maddison, Albrighton, Amartey, Iborra, Silva, Mendy, Ndidi, Ghezzal, Choudhury, Iheanacho, Diabate, Okazaki.
Wolverhampton v Southampton, 3pm
Wolves are likely to revert back to the same side who have started their previous six Premier League games.
It would mean record buy Adama Traore would again have to settle for a place on the bench following his £18million move from Middlesbrough.
Ivan Cavaleiro (back) and Leander Dendoncker (match fitness) have yet to feature in the league but both played in Tuesday's Carabao Cup penalty defeat to Leicester and are available.
Provisional squad: Patricio, Ruddy, Norris, Doherty, Bennett, Boly, Coady, Gibbs-White, Otto, Hause, Dendoncker, Neves, Costa, Enobakhare, Diogo, Saiss, Moutinho, Vinagre, Bonatini, Jimenez, Traore, Cavaleiro.
Southampton will welcome back on-loan forward Danny Ings for the Premier League trip to Wolves.
Ings, who has scored three times this season, was not eligible for last week's match at Liverpool under the terms of his season-long switch.
Republic of Ireland forward Shane Long, though, is a major doubt because of a toe problem, but both Manolo Gabbiadini (hamstring) and Moi Elyounoussi should be available after returning to training.
Provisional Squad: McCarthy, Soares, Vestergaard, Hoedt, Bertrand, Targett, Romeu, Lemina, Redmond, Hojbjerg, Ings, Gunn, Yoshida, Bednarek, Davis, Ward-Prowse, Armstrong, Austin, Gabbiadini, Elyounoussi, Long
Chelsea v Liverpool, 5.30pm
Andreas Christensen should be fit for Chelsea's Premier League clash with Liverpool on Saturday after shaking off a stomach bug.
Antonio Rudiger, Pedro and Ruben Loftus-Cheek will all be given late fitness tests ahead of the Stamford Bridge encounter, however.
Rudiger (groin), Pedro (shoulder) and Loftus Cheek (shin) must still prove their fitness, but are all back in training.
Provisional squad: Kepa, Caballero, Rudiger, Alonso, Fabregas, Jorginho, Kante, Barkley, Hazard, Pedro, Loftus-Cheek, Moses, Giroud, Zappacosta, Willian, Cahill, Christensen, Azpilicueta, Morata, Luiz, Emerson Palmieri, Ampadu, Hudson-Odoi, Bulka.
Virgil van Dijk is a major injury doubt for Liverpool's fixture at Chelsea.
Liverpool's record signing aggravated a rib problem in the Reds' 3-0 victory over Southampton last week and has not trained with the first team since, so Dejan Lovren could start at the back at Stamford Bridge.
Trent Alexander-Arnold and Georginio Wijnaldum have recovered from a knock and illness, respectively, for a game in which manager Jurgen Klopp will bring back his regulars after fielding a largely second string side in a Carabao Cup defeat to the Blues in midweek.
Provisional squad: Alisson, Mignolet, Alexander-Arnold, Gomez, Van Dijk, Lovren, Robertson, Wijnaldum, Milner, Keita, Salah, Firmino, Mane, Clyne, Matip, Moreno, Henderson, Fabinho, Shaqiri, Solanke, Sturridge.
Sunday, September 30
Cardiff City v Burnley, 4pm
Lee Peltier starts a lengthy spell on the sidelines as Cardiff host Burnley in the Premier League on Sunday.
The defender is facing two to three months out after dislocating a shoulder against Manchester City last weekend, but the defender will not require an operation as the injury will heal naturally.
Aron Gunnarsson (knee) remains out, but Sol Bamba is expected to return in defence with Bruno Ecuele Manga moving to right back in Peltier's absence.
Provisional squad: Etheridge, Smithies, Richards, Cunningham, Morrison, Bamba, Connolly, Manga, Bennett, Arter, Damour, Ralls, Camarasa, Paterson, Hoilett, Murphy, Reid, Zohore, Ward, Madine.
Steven Defour could feature in the Burnley side for their Premier League trip to Cardiff on Sunday.
PREVIEW | "We've got to go and earn the right, yet again"September 28, 2018
The Belgium international played for the first time since January in the midweek Carabao Cup defeat at Burton.
Ben Gibson (hernia) is still ruled out while Robbie Brady (knee) is making good progress and expected to return to action within the next fortnight.
Provisional squad: Hart, Heaton, Lowton, Taylor, Tarkowski, Mee, Ward, Bardsley, Long, Cork, Gudmundsson, Hendrick, Westwood, Lennon, McNeil, Vokes, Defour, Barnes, Wood, Vydra.
Monday, October 1
Bournemouth v Crystal Palace, 8pm
Bournemouth will check on defender Diego Rico (hamstring) and midfielder Dan Gosling (calf) ahead of Monday night's Premier League match against Crystal Palace.
🔺 Rico and Gosling doubts.
🔺 Daniels back in training.
🔺 Taylor still out.September 28, 2018
Left-back Charlie Daniels is closing in on a return from his knee problem.
Midfielder Kyle Taylor (calf) remains unavailable.
Provisional Squad: Begovic, S Cook, Ake, Smith, Rico, Surman, Lerma, Brooks, Fraser, Wilson, King, Boruc, Francis, Mings, Ibe, L Cook, Stanislas, Defoe, Daniels, Gosling.
Christian Benteke remains Crystal Palace's only significant absentee for Monday's Premier League fixture at Bournemouth.
The striker remains sidelined with a knee injury, so Jordan Ayew is expected to continue to deputise.
Scott Dann and Connor Wickham continue their recoveries from long-term knee injuries, while Jairo Riedewald misses out with a knock.
Team from: Hennessey, Guaita, Speroni, Wan-Bissaka, Ward, Tomkins, Sakho, Kelly, Van Aanholt, Souare, Townsend, Kouyate, McArthur, Meyer, Milivojevic, Puncheon, Schlupp, Ayew, Kaikai, Sorloth, Zaha.
- Digital Desk and PA