Patrick ‘Bonner’ Maher is a notable omission from the Tipperary team that will face Cork on Sunday.
The 2014 All-Star centre-forward, who missed Tipp’s final League game with a knee injury, is left out of a side which features four debutants, three of which are in attack.
Sean Curran and Dan McCormack come into the half-forward line, with Maher, Niall O'Meara and Silvermines forward Jason Forde among those missing out.
Loughmore-Castleiney brothers Noel and John McGrath, who both missed much of last season through illness and injury, are named on the left flank of the Tipp attack.
John, who has won minor All-Irelands in hurling and football, makes his Championship debut.
In all, the team features seven changes from last year’s All-Ireland semi-final against Galway.
Michael Cahill comes in at left-corner back and is joined in defence by code-changing debutant Seamus Kennedy, who lined out for the Tipp footballers last year.
All six defenders are alumni of schools hurling powerhouse Thurles CBS.
The Premier county are particularly strong at midfield as captain Brendan Maher is joined by the hugely progressive Michael Breen.
In attack, Seamus Callanan will be utilised as a devastating target-man once more at full-forward for the 4/11 shots and his tussles with Mark Ellis and/or Christopher Joyce could be contest-defining.
The team in full is:
1 Darren Gleeson - Portroe
2 Cathal Barrett - Holycross-Ballycahill
3 James Barry - Upperchurch-Drombane
4 Michael Cahill - Thurles Sarsfields
5 Seamus Kennedy - St. Mary's
6 Ronan Maher - Thurles Sarsfields
7 Padraic Maher - Thurles Sarsfields
8 Brendan Maher (Capt.) - Borris-Ileigh
9 Michael Breen - Ballina
10 Sean Curran - Mullinahone
11 Dan McCormack - Borris-Ileigh
12 Noel McGrath - Loughmore-Castleiney
13 John O’Dwyer - Killenaule
14 Seamus Callanan - Drom & Inch
15 John McGrath - Loughmore-Castleiney