Manchester United captain Gary Neville has been added to the list of players who will miss the club’s summer tour and have treatment at Carrington instead.
The 35-year-old defender is suffering from a calf problem but could be fit for the start of the season.
Also staying behind for treatment at the club’s training base are Rio Ferdinand (knee), Michael Owen (hamstring), Antonio Valencia (ankle) and Anderson (knee).
Neville recovered strongly last season after injuries had curtailed his involvement in previous years and was handed a 12-month extension to his contract.
United say he suffered a minor setback in training with a small tear to his calf muscle.
Manager Alex Ferguson believes it will be more beneficial for Neville to remain at home to improve his chances of being ready for the Barclays Premier League campaign.
Veteran pair Ryan Giggs and Paul Scholes will lead the 22-man party on the four-match tour, with United flying out on Monday to their training camp in Chicago and then moving on to face Celtic in Toronto next Friday.
Edwin van der Sar, Darren Fletcher and Dimitar Berbatov will also travel, along with some promising youngsters including former Fulham defender Chris Smalling.
Portugal forward Nani is also included after making a quick recovery from a broken collarbone which caused him to come home early from the World Cup.
United meet Philadelphia Union at Lincoln Financial Field on July 21, followed by a match against the Kansas City Wizards at Arrowhead Stadium on July 25.
They then finish the tour against the MLS All-Stars in Houston on July 28.
Darren Fletcher is looking forward to the tour, telling MUTV: “It’s a great tour in America. We’ve not been there in a while.
“Although three weeks is going to be a long time to be away, there’ll be some good games. Personally, playing against Celtic [in Toronto] will be interesting as I’ll be up against a few of my Scottish team-mates. But I’m looking forward to it all really.”