Munster have made five changes to the team that beat the Ospreys with a number of academy players in the mix.
Jack O'Donoghue and Rory Scannell will miss out over injury with Conor Oliver coming into the back-row and Dan Goggin taking the open spot in the centre.
Jaco Taute has been passed fit and starts at full back with Darren Sweetnam and Ronan O'Mahony filling the wings.
Francis Saili, cleared to play after being cited against Ospreys, joins Goggin in the centre, with Tyler Bleyendaal and Duncan Williams continuing as half-backs.
Stephen Archer starts in the front row alongside Rhys Marshall and Dave Kilcoyne with Dave Foley and Billy Holland supporting them in second-row.
In the back row, Oliver takes his place at number 8 with Dave O'Callaghan and Tommy O'Donnell either side of him.
5 changes for #MUNvSCA The academy's @ConorOliver makes 1st start at 8 & @FineenWych named in1st PRO12 squad. https://t.co/1HUj2kAb7z pic.twitter.com/Rz1JRkSEFB— Munster Rugby (@Munsterrugby) February 23, 2017
The bench includes 19-year-old Fineen Wycherley in his first PRO12 squad and Ian Keatley and Andrew Conway return from Ireland camp to be named in the match-day 23.
Munster: Jaco Taute; Darren Sweetnam, Francis Saili, Dan Goggin, Ronan O'Mahony; Tyler Bleyendaal Capt., Duncan Williams; Dave Kilcoyne, Rhys Marshall, Stephen Archer; Dave Foley, Billy Holland; Dave O'Callaghan, Tommy O'Donnell, Conor Oliver.
Replacements: Kevin O'Byrne, Peter McCabe, Brian Scott, Darren O'Shea, Fineen Wycherley, Abrie Griesel, Ian Keatley, Andrew Conway.