Everton have made three changes from the side that beat AEK Athens 4-0 on Thursday in the Europa League with Dutch defender John Heitinga making his home debut.
Russian winger Diniyar Bilyaletdinov is out with a groin strain while Jo and Dan Gosling drop to the bench to allow Louis Saha and Leon Osman into the starting line-up.
Blackburn have given Spanish defender Michel Salgado his full debut in an otherwise unchanged side from the one that achieved the club’s first league win of the season against Wolves last time out.
Everton: Howard, Heitinga, Yobo, Distin, Baines, Osman, Rodwell, Cahill, Pienaar, Fellaini, Saha.
Subs: Nash, Hibbert, Jo, Gosling, Yakubu, Agard, Wallace.
Blackburn: Robinson, Salgado, Samba, Givet, Chimbonda, Andrews, Grella, Diouf, Dunn, Pedersen, Roberts.
Subs: Brown, Nelsen, Emerton, McCarthy, Nzonzi, Kalinic, Hoilett.
Referee: Lee Mason.