UEFA today confirmed that Dublin's Aviva Stadium will share Group E duties with Bilbao in Euro 2020.
Qualified host nations are guaranteed two games at home.
Should they qualify, the Republic of Ireland will be in Group E of the tournament.
The FAI said four matches will be played in the Aviva, which FAI CEO John Delaney welcomed.
He said: "Today's host city pairings marks an exciting chapter in the build-up to the European Championships, which will see Dublin and Ireland hosting the biggest ever sporting event to take place in our country.
"A huge amount of work has gone into preparation for the tournament and we are making enormous progress in preparing the Aviva Stadium for when it becomes a focus for worldwide attention during this prestigious competition.
"I look forward to welcoming our friends from Bilbao to Dublin where we can build a strong partnership working together to ensure the very best organisational and sporting structures are in place for the summer of 2020."
Meanwhile, London will host seven games during the multi-city tournament after UEFA handed the four fixtures scheduled for Brussels to Wembley today.
UEFA decided to reallocate the three group-stage games and one last-16 game originally given to the Belgian capital because of delays in the project to build a new 60,000-capacity Eurostadium on the site of Heysel.
Cardiff's Principality Stadium and Stockholm's Friends Arena - the venues for last season's finals of the Champions League and Europa League, respectively - had hoped to pick up Brussels' games.
However, UEFA opted for Wembley, which has already been chosen as the venue for the semi-finals and final.
Speaking at a press conference in Nyon, which was broadcast on its website, UEFA president Aleksander Ceferin said the decision to take the games from Brussels was unanimous after the Belgian authorities failed to provide guarantees the new stadium would be ready.
Glasgow's Hampden Park had been hoping to stage the tournament's opening game but that honour has gone to Rome's Stadio Olimpico.
Staged across 12 countries, Euro 2020's unusual format was former UEFA president Michel Platini's brainchild - a one-off gesture to celebrate the tournament's 60th birthday.
As well as deciding where the first game, on June 12, will be and what to do about Brussel's difficulties, the executive committee also announced where each of the six groups' games will be played.
Baku and Rome will host group A, group B's games will take place in Copenhagen and St Petersburg, Amsterdam and Bucharest get group C, Glasgow and London will share group D, group E will be staged in Bilbao and Dublin, while group F's fixtures will be in Budapest and Munich.