UCD team tackles antibiotic resistance

UCD team tackles antibiotic resistance

Common antibiotics could be “resuscitated” to make them more effective against resistant bugs, say researchers from University College Dublin (UCD).

The technique involves combining the drugs with additional compounds.

Scientists from UCD studied a range of hospital-sampled bacteria that were resistant to the common antibiotic ciprofloxacin.

Tests showed that five “adjuvant” compounds increased the power of ciprofloxacin to defeat the bugs up to six-fold.

Lead researcher Dr Marta Martins said: “Antimicrobial resistance is a growing problem that is threatening to make many infections impossible to treat. There are very few new antibacterial drugs coming on to the market so it is vital that we find ways to extend the use of existing antibiotics as much as possible.

“Adjuvant therapy essentially means that antibiotics that are currently ineffective can be ’resuscitated’ to treat infections that previously would have been considered resistant.”

The research was presented at the Society for General Microbiology’s spring conference in Dublin.

Dr Martins added: “Hopefully this work will allow antibiotics to be incorporated into treatment regimes and administered in more effective ways.

“As well as extending the lifespan of current antibiotics, this approach could ultimately reduce levels of antimicrobial resistance in hospitals as well as in the community, allowing hard-to-treat bacterial infections to be successfully controlled.”

The bugs studied included strains of Pseudomonas, Klebsiella, Enterobacter and Staphylococcus.

More in this Section

Irish don’t understand HPV, says researchIrish don’t understand HPV, says research

Impasse persists at beef sector talksImpasse persists at beef sector talks

UCC scientists discover new way to reconstruct what extinct animals looked likeUCC scientists discover new way to reconstruct what extinct animals looked like

Thousands celebrate Tipperary All-Ireland Success in ThurlesThousands celebrate Tipperary All-Ireland Success in Thurles


Lifestyle

Timothy Grady is in Bantry this week to host a concert, and read from his classic book about the Irish in London, writes Don O'Mahony.Giving voice to the emigrant experience

A care home builds links with kids, writes Helen O’Callaghan.Inside out: Children learn what it's like to live with dementia.

When you think of someone who is “into skincare”, you probably imagine someone in a face mask.The Skin Nerd: Why face masks aren’t as important as you’d think

With the evenings closing in and a welcome chill in the air, it’s time to embrace the new season now.Make the Transition: Turn over a new leaf this fall

More From The Irish Examiner