Staff who are on long-term sick leave will be able to build up annual leave from work, from today.
It follows rulings by the European Court of Justice regarding annual leave entitlements during long-term illness.
Minister for Business and Employment Ged Nash explained what the changes mean.
He said: "It will really mean that workers in Ireland will be able to carry over any annual leave that they have built up during a period of long-term sick leave.
"They'll be able to carry that over for a period of 15 months after the sick leave year in question."