The Dáil now looks set to sit into the early hours of the morning to complete the passage of the abortion legislation.
European Affairs Minister Lucinda Creighton is expected to vote against the legislation when her amendments are rejected later tonight.
Earlier the Health Minister refused to accept amendments calling for the legislation to be less restrictive.
James Reilly insisted he was willing to debate this legislation for as long as people wanted.
"I don't believe there has been another bill in the history of this state that has received so much attention and so much time," he said.
"It is certainly not this government's intention to shorten this debate in anyway, but there has to be a time limit at some point
"We'll sit until 12 and as the day evolves I personally have no problem staying here all night and all morning on this subject."