1,245 new jobs have been announced at four separate companies this morning.
Some 800 positions are being created at Nua Healthcare over the next three years.
The jobs are in new residential and day care facilities around the country for people with intellectual disabilities.
Environmental services company Veolia is creating 300 positions over the next five years at its operations across Ireland.
Another 100 high-tech jobs have been confirmed at online marketing company Boxever in Dublin.
Some 45 positions have been announced at online research company Netigate in Cork.
Nua Healthcare said the 20 private disability care homes will be constructed in the south of the country over the coming three years.
The expansion plans were revealed at the official opening of the private operator’s Glenview House in Kilmallock, Co Limerick.
The six-bed facility will be staffed by up to 30 carers giving round-the-clock support to adults with special needs.
Nua Healthcare said 300 of the jobs will be created this year as part of its three-year expansion plan.
Edward Dunne, chief executive of the company, said the investment was down to huge demand for their services over recent years.
“Today’s announcement is a major step towards making our service more accessible to individuals nationally,” he said.
“The ability to do so is testament to the incredible work of our committed team and partners in such a specialist sector.”
Nua Healthcare already employs more than 800 staff at 28 locations around the country.
Veolia Ireland country director Pat Gilroy said the company would be creating 300 jobs over the next five years as the company targets double digit growth.
"As we transition to a low carbon economy, it is imperative that companies can access environmentally sustainable solutions," he said.
"We are setting out to do just that, providing businesses in Ireland with the means to manage their resource needs more efficiently and grow with us in a circular economy.
"Following a recent €450m deal, we are already set to operate Mayo Renewable Power, Ireland’s largest independent biomass power plant which opens in 2017 that will help provide Ireland with 6% of its renewable energy needs."
Boxever plans to create 100 new jobs primarily among data scientists & software engineers in Dublin.
The company provides "data science and omni-channel personalization solutions" for clients including Aer Lingus and Emirates.
In January 2016, Netigate opened up a new international office in Cork, Ireland
"In 2016 we will continue focusing on product development”, says Tobias Thalbäck, CEO of Netigate.
"We have a lot of exciting news for all our customers, existing and new.
"Netigate will continue to deliver the most powerful, and easiest-to-use survey and insight platform on the market."