Rock groups Muse and The Verve will headline the V Festival this weekend.
Music fans are promised a varied line-up over five stages ranging from dance pioneers The Chemical Brothers to troubled soul singer Amy Winehouse.
Forecasters are predicting a mixture of cool weather and showers at the event's two sites at Hylands Park in Chelmsford, Essex, and Weston Park, Staffordshire.
In their only European festival appearances this year, Muse are expected to live up to their reputation for spectacular performances.
Their V appearance concludes a gruelling world tour, after which the Devon three-piece will return to the studio to begin the follow-up to 2006's 'Black Holes and Revelations' album.
Recently reformed Wigan rockers The Verve were this week forced to deny rumours that they would be pulling out of the festival after guitarist Nick McCabe injured his finger at a recent show in Japan.
They will play material from new album 'Forth' as well as hits like 'Bittersweet Symphony' and 'The Drugs Don't Work'.
Muse top the bill at Hylands Park and The Verve headline Weston Park today, but the entire line-up swaps venues overnight.
Winehouse will be hoping to put behind her recent troubles and win over the crowds with fan favourite like 'Rehab' and 'You Know I'm No Good'.
Last month the 24-year-old Grammy winner was hospitalised overnight after reacting badly to medication and her husband Blake Fielder-Civil was jailed for trying to cover up an attack on a pub landlord.
Elsewhere the bill is shared by a mixture of pop, rock and urban acts including Stereophonics, The Kooks, Kings of Leon, Girls Aloud, Will Young, Roots Manuva, Guillemots, Ian Brown, Estelle and The Zutons.
The festival, now in its 13th year, sold out in just 90 minutes when tickets went on sale in March.
The event is being broadcast on Virgin Radio.