Update 10am: Forty new jobs have been announced in Dublin at pharmaceuticals company Mallonckrodt.
The company announced a new €10m R&D centre in the capital.
It will bring their workforce in Ireland to 120 by 2017.
Meanwhile, US developer of mathematical computing software for engineers and scientists MathWorks has announced 50 jobs at a new centre in Galway.
100 new jobs are to be created by Irish healthcare company Oneview Healthcare.
Half of the new positions will be based in Dublin and the other half across the company's international offices.
President of Oneview Healthcare Mark McCluskey said the company is expanding into a different market.
"We're already in the hospital market, and we're moving into the senior-living market," he said.
The jobs in Dublin will primarily be in development and in solutions-development. The jobs in the US and Australia will be for sales, system integration and solutions consultants."