Manchester United will face Chelsea in a mouth-watering FA Cup quarter-final if both clubs progress through their respective fifth-round ties.
Chelsea must overcome Middlesbrough on February 27 with the winner taking on either United or Reading, who face each other tonight.
The Blues, who are looking to win the competition for a fourth time in five years, secured their place in round five with a 4-0 replay defeat of Brentford.
Elsewhere, if Oldham can defeat Everton then they will host Wigan Athletic.
Premier League champions Manchester City host Barnsley, while Millwall are at home to Blackburn.
With City’s Premier League campaign faltering and the club already out of Europe, manager Roberto Mancini knows the FA Cup takes on extra importance.
"Every team plays in the FA Cup like it is in a Champions League final," he said.
"The cup is an important trophy in England. Teams may change players in the Capital One Cup but in the FA Cup every team plays seriously.
"You could play in a final at Wembley in front of more than 80,000 people so that has to be good."